43 research outputs found

    Monochromatic coherent transition and diffraction radiation from a relativistic electron bunch train

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    Electron beams of most accelerators have a bunched structure and are synchronized with the accelerating RF field. Due to modulation of the electron beam with frequency v[RF] one can expect to observe resonances with frequencies vk= k·v[RF] in radiation spectrum generated via any spontaneous emission mechanism (k is an integer and the resonance order). In this paper we present the results of spectral measurements of coherent transition radiation (CTR) generated by an electron bunch train from the Tomsk microtron with v[RF]=2.63GHz in the spectral frequency range from 8 to 35 GHz. We also measured the spectrum of coherent diffraction radiation and demonstrated that the observed spectra in both cases consist of monochromatic lines. For spectral measurements the Martin-Puplett interferometer with spectral resolution of 800 MHz (FWMH) was employed. Using a waveguide frequency cut-off we were able to exclude several spectral lines to observe higher resonance orders of up to k=7

    Monochromaticity of coherent Smith-Purcell radiation from finite size grating

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    Investigation of coherent Smith-Purcell Radiation (SPR) spectral characteristics was performed both experimentally and by numerical simulation. The measurement of SPR spectral line shapes of different diffraction orders was carried out at KEK LUCX facility. A pair of room-temperature Schottky barrier diode (SBD) detectors with sensitivity bands of 609060-90~GHz and 320460320-460~GHz was used in the measurements. Reasonable agreement of experimental results and simulations performed with CST Studio Suite justifies the use of different narrow-band SBD detectors to investigate different SPR diffraction orders. It was shown that monochromaticity of the SPR spectral lines increases with diffraction order. The comparison of coherent transition radiation and coherent SPR intensities in sub-THz frequency range showed that the brightnesses of both radiation mechanisms were comparable. A fine tuning feasibility of the SPR spectral lines is discussed.Comment: 7 pages, 7 figures, 3 table

    Natural Selection Equally Supports the Human Tendencies in Subordination and Domination: A Genome-Wide Study With in silico Confirmation and in vivo Validation in Mice

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    We proposed the following heuristic decision-making rule: “IF {an excess of a protein relating to the nervous system is an experimentally known physiological marker of low pain sensitivity, fast postinjury recovery, or aggressive, risk/novelty-seeking, anesthetic-like, or similar agonistic-intolerant behavior} AND IF {a single nucleotide polymorphism (SNP) causes overexpression of the gene encoding this protein} THEN {this SNP can be a SNP marker of the tendency in dominance} WHILE {underexpression corresponds to subordination} AND vice versa.” Using this decision-making rule, we analyzed 231 human genes of neuropeptidergic, non-neuropeptidergic, and neurotrophinergic systems that encode neurotrophic and growth factors, interleukins, neurotransmitters, receptors, transporters, and enzymes. These proteins are known as key factors of human social behavior. We analyzed all the 5,052 SNPs within the 70 bp promoter region upstream of the position where the protein-coding transcript starts, which were retrieved from databases Ensembl and dbSNP using our previously created public Web service SNP_TATA_Comparator (http://beehive.bionet.nsc.ru/cgi-bin/mgs/tatascan/start.pl). This definition of the promoter region includes all TATA-binding protein (TBP)-binding sites. A total of 556 and 552 candidate SNP markers contributing to the dominance and the subordination, respectively, were uncovered. On this basis, we determined that 231 human genes under study are subject to natural selection against underexpression (significance p < 0.0005), which equally supports the human tendencies in domination and subordination such as the norm of a reaction (plasticity) of the human social hierarchy. These findings explain vertical transmission of domination and subordination traits previously observed in rodent models. Thus, the results of this study equally support both sides of the century-old unsettled scientific debate on whether both aggressiveness and the social hierarchy among humans are inherited (as suggested by Freud and Lorenz) or are due to non-genetic social education, when the children are influenced by older individuals across generations (as proposed by Berkowitz and Fromm)

    Phylogenomics revealed migration routes and adaptive radiation timing of holarctic malaria mosquito species of the Maculipennis group

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    BackgroundPhylogenetic analyses of closely related species of mosquitoes are important for better understanding the evolution of traits contributing to transmission of vector-borne diseases. Six out of 41 dominant malaria vectors of the genus Anopheles in the world belong to the Maculipennis Group, which is subdivided into two Nearctic subgroups (Freeborni and Quadrimaculatus) and one Palearctic (Maculipennis) subgroup. Although previous studies considered the Nearctic subgroups as ancestral, details about their relationship with the Palearctic subgroup, and their migration times and routes from North America to Eurasia remain controversial. The Palearctic species An. beklemishevi is currently included in the Nearctic Quadrimaculatus subgroup adding to the uncertainties in mosquito systematics.ResultsTo reconstruct historic relationships in the Maculipennis Group, we conducted a phylogenomic analysis of 11 Palearctic and 2 Nearctic species based on sequences of 1271 orthologous genes. The analysis indicated that the Palearctic species An. beklemishevi clusters together with other Eurasian species and represents a basal lineage among them. Also, An. beklemishevi is related more closely to An. freeborni, which inhabits the Western United States, rather than to An. quadrimaculatus, a species from the Eastern United States. The time-calibrated tree suggests a migration of mosquitoes in the Maculipennis Group from North America to Eurasia about 20-25 million years ago through the Bering Land Bridge. A Hybridcheck analysis demonstrated highly significant signatures of introgression events between allopatric species An. labranchiae and An. beklemishevi. The analysis also identified ancestral introgression events between An. sacharovi and its Nearctic relative An. freeborni despite their current geographic isolation. The reconstructed phylogeny suggests that vector competence and the ability to enter complete diapause during winter evolved independently in different lineages of the Maculipennis Group.ConclusionsOur phylogenomic analyses reveal migration routes and adaptive radiation timing of Holarctic malaria vectors and strongly support the inclusion of An. beklemishevi into the Maculipennis Subgroup. Detailed knowledge of the evolutionary history of the Maculipennis Subgroup provides a framework for examining the genomic changes related to ecological adaptation and susceptibility to human pathogens. These genomic variations may inform researchers about similar changes in the future providing insights into the patterns of disease transmission in Eurasia

    Rapid and highly variable warming of lake surface waters around the globe

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    In this first worldwide synthesis of in situ and satellite-derived lake data, we find that lake summer surface water temperatures rose rapidly (global mean = 0.34°C decade-1) between 1985 and 2009. Our analyses show that surface water warming rates are dependent on combinations of climate and local characteristics, rather than just lake location, leading to the counterintuitive result that regional consistency in lake warming is the exception, rather than the rule. The most rapidly warming lakes are widely geographically distributed, and their warming is associated with interactions among different climatic factors - from seasonally ice-covered lakes in areas where temperature and solar radiation are increasing while cloud cover is diminishing (0.72°C decade-1) to ice-free lakes experiencing increases in air temperature and solar radiation (0.53°C decade-1). The pervasive and rapid warming observed here signals the urgent need to incorporate climate impacts into vulnerability assessments and adaptation efforts for lakes

    Lake Ladoga Digital Bathymetric Models: Development Approaches and Insight for Limnological Investigations

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    The creation of digital bathymetric models (DBM) of lakes allows not only for storage of the data on depths and shorelines in a standard format, but also for the estimation of the major morphometric characteristics of the reservoirs. To calculate the water, thermal, and chemical budgets of large lakes, it is important to know their hypsometry. We developed a new digital model of Lake Ladoga, the largest European lake, which was done to identify and correct topographic data errors, as well as to identify more depth points. The produced bathymetric model of the lake allowed for the updating of morphometric characteristics. The lake-bottom grid of 0.5×0.5 km with 70190 depth points of interest was produced using the kriging procedure with the mean error ME = 0.05 m and root mean square error RMSE = 5.6 m. The statistical characteristics of the lake depth and slope are determined on the basis of the advanced digital model of the lakebed relief. The form of the lake depression corresponds to the convex type (microtype) and bears some similarity to lakes Erie, Huron, Vanern, and Malaren. We describe how the bathymetric model has been developed and the morphometric characteristics of the lake have been corrected. We also discuss the results of its application in limnological investigations. A relationship has been established between surface water temperature, transparency and the bottom depths for the various seasons of Lake Ladoga
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